Karl-Johan Malmberg, List of Publications, Last 8 years
Original articles (1-27)
1.
Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B,
Theodorou I, Martinot M, Debre P, Bjorkstrom NK, Malmberg KJ, Marcellin P,
Vieillard V. CMV drives clonal expansion of NKG2C+ NK cells expressing selfspecific KIRs in chronic hepatitis patients. Eur J Immunol. 2012;42(2):447-57.
2.
Taner SB, Pando MJ, Roberts A, Schellekens J, Marsh SG, Malmberg KJ,
Parham P, Brodsky FM. Interactions of NK cell receptor KIR3DL1*004 with
chaperones and conformation-specific antibody reveal a functional folded state
as well as predominant intracellular retention. J Immunol. 2011;186(1):62-72.
3.
Remberger M, Ackefors M, Berglund S, Blennow O, Dahllof G, Dlugosz A,
Garming-Legert K, Gertow J, Gustafsson B, Hassan M, Hassan Z, Hauzenberger D,
Hagglund H, Karlsson H, Klingspor L, Kumlien G, Le Blanc K, Ljungman P,
Machaczka M, Malmberg KJ, Marschall HU, Mattsson J, Olsson R, Omazic B, Sairafi
D, Schaffer M, Svahn BM, Svenberg P, Swartling L, Szakos A, Uhlin M, Uzunel M,
Watz E, Wernerson A, Wikman A, Wikstrom AC, Winiarski J, Ringden O.
Improved survival after allogeneic hematopoietic stem cell transplantation in
recent years. A single-center study. Biol Blood Marrow Transplant.
2011;17(11):1688-97.
4.
Kuylenstierna C, Bjorkstrom NK, Andersson SK, Sahlstrom P, Bosnjak L,
Paquin-Proulx D, Malmberg KJ, Ljunggren HG, Moll M, Sandberg JK. NKG2D
performs two functions in invariant NKT cells: direct TCR-independent
activation of NK-like cytolysis and co-stimulation of activation by CD1d. Eur J
Immunol. 2011;41(7):1913-23.
5.
Enqvist M, Nilsonne G, Hammarfjord O, Wallin RP, Bjorkstrom NK,
Bjornstedt M, Hjerpe A, Ljunggren HG, Dobra K, Malmberg KJ, Carlsten M.
Selenite induces posttranscriptional blockade of HLA-E expression and sensitizes
tumor cells to CD94/NKG2A-positive NK cells. J Immunol. 2011;187(7):3546-54.
6.
Bjorkstrom NK, Svensson A, Malmberg KJ, Eriksson K, Ljunggren HG.
Characterization of natural killer cell phenotype and function during recurrent
human HSV-2 infection. PLoS One. 2011;6(11):e27664.
7.
Bjorkstrom NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M,
Michaelsson J, Malmberg KJ, Klingstrom J, Ahlm C, Ljunggren HG. Rapid
expansion and long-term persistence of elevated NK cell numbers in humans
infected with hantavirus. J Exp Med. 2011;208(1):13-21.
8.
Schellekens J, Schaffer M, Malmberg KJ, Madrigal JA, Marsh SG.
Identification of a novel KIR3DL1*072 allele by sequence-based typing. Tissue
Antigens. 2010;76(1):74-5.
9.
Rotzius P, Thams S, Soehnlein O, Kenne E, Tseng CN, Bjorkstrom NK,
Malmberg KJ, Lindbom L, Eriksson EE. Distinct infiltration of neutrophils in
lesion shoulders in ApoE-/- mice. Am J Pathol. 2010;177(1):493-500.
10.
Fauriat C, Ivarsson MA, Ljunggren HG, Malmberg KJ, Michaelsson J.
Education of human natural killer cells by activating killer cell immunoglobulinlike receptors. Blood. 2010;115(6):1166-74.
11.
Fasth AE, Bjorkstrom NK, Anthoni M, Malmberg KJ, Malmstrom V.
Activating NK-cell receptors co-stimulate CD4(+)CD28(-) T cells in patients with
rheumatoid arthritis. Eur J Immunol. 2010;40(2):378-87.
12.
Carlsten M, Baumann BC, Simonsson M, Jadersten M, Forsblom AM,
Hammarstedt C, Bryceson YT, Ljunggren HG, Hellstrom-Lindberg E, Malmberg KJ.
Reduced DNAM-1 expression on bone marrow NK cells associated with impaired
killing of CD34+ blasts in myelodysplastic syndrome. Leukemia.
2010;24(9):1607-16.
13.
Bjorkstrom NK, Riese P, Heuts F, Andersson S, Fauriat C, Ivarsson MA,
Bjorklund AT, Flodstrom-Tullberg M, Michaelsson J, Rottenberg ME, Guzman CA,
Ljunggren HG, Malmberg KJ. Expression patterns of NKG2A, KIR, and CD57
define a process of CD56dim NK-cell differentiation uncoupled from NK-cell
education. Blood. 2010;116(19):3853-64.
14.
Bjorklund AT, Schaffer M, Fauriat C, Ringden O, Remberger M,
Hammarstedt C, Barrett AJ, Ljungman P, Ljunggren HG, Malmberg KJ. NK cells
expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched
sibling stem cell transplantation. Blood. 2010;115(13):2686-94.
15.
Fasth AE, Dastmalchi M, Rahbar A, Salomonsson S, Pandya JM, Lindroos E,
Nennesmo I, Malmberg KJ, Soderberg-Naucler C, Trollmo C, Lundberg IE,
Malmstrom V. T cell infiltrates in the muscles of patients with dermatomyositis
and polymyositis are dominated by CD28null T cells. J Immunol.
2009;183(7):4792-9.
16.
Curbo S, Gaudin R, Carlsten M, Malmberg KJ, Troye-Blomberg M, Ahlborg
N, Karlsson A, Johansson M, Lundberg M. Regulation of interleukin-4 signaling by
extracellular reduction of intramolecular disulfides. Biochem Biophys Res
Commun. 2009;390(4):1272-7.
17.
Carlsten M, Norell H, Bryceson YT, Poschke I, Schedvins K, Ljunggren HG,
Kiessling R, Malmberg KJ. Primary human tumor cells expressing CD155 impair
tumor targeting by down-regulating DNAM-1 on NK cells. J Immunol.
2009;183(8):4921-30.
18.
Andersson S, Fauriat C, Malmberg JA, Ljunggren HG, Malmberg KJ. KIR
acquisition probabilities are independent of self-HLA class I ligands and increase
with cellular KIR expression. Blood. 2009;114(1):95-104.
19.
Huhn MH, Hultcrantz M, Lind K, Ljunggren HG, Malmberg KJ, FlodstromTullberg M. IFN-gamma production dominates the early human natural killer cell
response to Coxsackievirus infection. Cell Microbiol. 2008;10(2):426-36.
20.
Fauriat C, Andersson S, Bjorklund AT, Carlsten M, Schaffer M, Bjorkstrom
NK, Baumann BC, Michaelsson J, Ljunggren HG, Malmberg KJ. Estimation of the
size of the alloreactive NK cell repertoire: studies in individuals homozygous for
the group A KIR haplotype. J Immunol. 2008;181(9):6010-9.
21.
Bjorkstrom NK, Gonzalez VD, Malmberg KJ, Falconer K, Alaeus A, Nowak
G, Jorns C, Ericzon BG, Weiland O, Sandberg JK, Ljunggren HG. Elevated numbers
of Fc gamma RIIIA+ (CD16+) effector CD8 T cells with NK cell-like function in
chronic hepatitis C virus infection. J Immunol. 2008;181(6):4219-28.
22.
Harlin H, Hanson M, Johansson CC, Sakurai D, Poschke I, Norell H,
Malmberg KJ, Kiessling R. The CD16- CD56(bright) NK cell subset is resistant to
reactive oxygen species produced by activated granulocytes and has higher
antioxidative capacity than the CD16+ CD56(dim) subset. J Immunol.
2007;179(7):4513-9.
23.
Hanson MG, Ozenci V, Carlsten MC, Glimelius BL, Frodin JE, Masucci G,
Malmberg KJ, Kiessling RV. A short-term dietary supplementation with high
doses of vitamin E increases NK cell cytolytic activity in advanced colorectal
cancer patients. Cancer Immunol Immunother. 2007;56(7):973-84.
24.
Carlsten M, Bjorkstrom NK, Norell H, Bryceson Y, van Hall T, Baumann BC,
Hanson M, Schedvins K, Kiessling R, Ljunggren HG, Malmberg KJ. DNAX accessory
molecule-1 mediated recognition of freshly isolated ovarian carcinoma by
resting natural killer cells. Cancer Res. 2007;67(3):1317-25.
25.
Norell H, Carlsten M, Ohlum T, Malmberg KJ, Masucci G, Schedvins K,
Altermann W, Handke D, Atkins D, Seliger B, Kiessling R. Frequent loss of HLA-A2
expression in metastasizing ovarian carcinomas associated with genomic
haplotype loss and HLA-A2-restricted HER-2/neu-specific immunity. Cancer
Res. 2006;66(12):6387-94.
26.
Takahashi A, Hanson MG, Norell HR, Havelka AM, Kono K, Malmberg KJ,
Kiessling RV. Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T
cells by hydrogen peroxide-induced oxidative stress. J Immunol.
2005;174(10):6080-7.
27.
Schaffer M, Malmberg KJ, Ringden O, Ljunggren HG, Remberger M.
Increased infection-related mortality in KIR-ligand-mismatched unrelated
allogeneic hematopoietic stem-cell transplantation. Transplantation.
2004;78(7):1081-5.
Peer reviewed reviews and book chapters
28.
Malmberg KJ, Michaelsson J, Parham P, Ljunggren HG. Killer cell
immunoglobulin-like receptor workshop: insights into evolution, genetics,
function, and translation. Immunity. 2011;35(5):653-7.
29.
Bjorkstrom NK, Fauriat C, Bryceson YT, Sandberg JK, Ljunggren HG,
Malmberg KJ. Analysis of the KIR repertoire in human NK cells by flow
cytometry. Methods Mol Biol. 2010;612:353-64.
30.
Andersson S, Malmberg JA, Malmberg KJ. Tolerant and diverse natural
killer cell repertoires in the absence of selection. Exp Cell Res.
2010;316(8):1309-15.
31.
Malmberg KJ, Ljunggren HG. Spotlight on IL-22-producing NK cell
receptor-expressing mucosal lymphocytes. Nat Immunol. 2009;10(1):11-2.
32.
Carlsten M, Malmberg KJ, Ljunggren HG. Natural killer cell-mediated lysis
of freshly isolated human tumor cells. Int J Cancer. 2009;124(4):757-62.
33.
Malmberg KJ, Bryceson YT, Carlsten M, Andersson S, Bjorklund A,
Bjorkstrom NK, Baumann BC, Fauriat C, Alici E, Dilber MS, Ljunggren HG. NK cellmediated targeting of human cancer and possibilities for new means of
immunotherapy. Cancer Immunol Immunother. 2008;57(10):1541-52.
34.
Gonzalez VD, Bjorkstrom NK, Malmberg KJ, Moll M, Kuylenstierna C,
Michaelsson J, Ljunggren HG, Sandberg JK. Application of nine-color flow
cytometry for detailed studies of the phenotypic complexity and functional
heterogeneity of human lymphocyte subsets. J Immunol Methods. 2008;330(12):64-74.
35.
Ljunggren HG, Malmberg KJ. Prospects for the use of NK cells in
immunotherapy of human cancer. Nat Rev Immunol. 2007;7(5):329-39.
36.
Malmberg KJ, Ljunggren HG. Escape from immune- and nonimmunemediated tumor surveillance. Semin Cancer Biol. 2006;16(1):16-31.
37.
Malmberg KJ, Schaffer M, Ringden O, Remberger M, Ljunggren HG. KIRligand mismatch in allogeneic hematopoietic stem cell transplantation. Mol
Immunol. 2005;42(4):531-4.
38.
Malmberg KJ. Effective immunotherapy against cancer: a question of
overcoming immune suppression and immune escape? Cancer Immunol
Immunother. 2004;53(10):879-92.
(28-38)
