Scientific publications by Siv Ahrné Original refereed scientific papers 1. GÖTZ F, AHRNÉ S, & LINDBERG M 1981 Plasmid transfer and genetic recombination by fusion in staphylococci. Journal of Bacteriology 145:74-81. 2. AXELSSON LT, AHRNÉ SEI, ANDERSSON MC, & STÅHL S 1988 Identification and cloning of a plasmid-encoded erythromycin-resistance determinant of Lactobacillus reuteri. Plasmid 20:171-174. 3. AHRNÉ S, MOLIN G, & STÅHL S 1989 Plasmids in Lactobacillus strains isolated from meat and meat products. Systematic and Applied Microbiology 11:320325. 4. LÖNNER C, PREVE-ÅKESSON K, & AHRNÉ S 1990 Plasmid contents of lactic acid bacteria isolated from different types of sour dough. Current Microbiology 20:201-207. 5. STÅHL M, MOLIN G, PERSSON A, AHRNÉ S, & STÅHL, S 1990 Restriction endonuclease and multivariate analysis as a classification tool for Lactobacillus spp. International Journal of Systematic Bacteriology 40:189-193. 6. AHRNÉ S & MOLIN G 1991 Spontaneous mutants changing the raffinose metabolism of Lactobacillus plantarum. Antonie van Leeuwenhoek 60:87-93. 7. AHRNÉ S 1991 Lactobacillus, a study of plasmids and strain stability (thesis). 8. MOLIN G, JOHANSSON M-L, STÅHL M, AHRNÉ S, ANDERSSON R, JEPPSSON B, & BENGMARK S 1992 Systematics of the Lactobacillus population on the rat intestinal mucosa with special reference to Lactobacillus reuteri. Antonie van Leeuwenhoek 61:175-183. 9. MOLIN G, ANDERSSON R, AHRNÉ S, LÖNNER C, MARKLINDER I, JOHANSSON M-L, JEPPSSON B, & BENGMARK S 1992 Effect of fermented oat meal soup on the cholesterol level and the Lactobacillus colonization of rat intestinal mucosa. Antonie van Leeuwenhoek 61: 167-173. 10. AHRNÉ S, CASAS I, LINDGREN S, MOLIN G, & DOBROGOSZ W 1992 Spontaneous and SDS-induced phenotype and plasmid alterations in Lactobacillus plantarum. Systematic and Applied Bacteriology 15:285-288. 11. AHRNÉ S, MOLIN G, & AXELSSON L 1992 Transformation of Lactobacillus reuteri with electroporation: studies on the erythromycin resistance plasmid pLUL631. Current Microbiology 24:199-205. 12. MOLIN G, JEPPSSON B, JOHANSSON M-L, NOBEAK S, AHRNÉ S, & BENGMARK S 1993 Numerical taxonomy of Lactobacillus spp. associated with healthy and diseased mucosa of the human intestines. Journal of Applied Bacteriology 74:314-323. 13. JOHANSSON M-L, MOLIN G, JEPPSSON B, NOBEAK S, AHRNÉ S, & BENGMARK S 1993 Administration of different Lactobacillus strains in fermented oat meal soup: In vivo colonization of human intestinal mucosa and effect on indigenous flora. Applied and Environmental Microbiology 59: 15-20. 14. STÅHL M, PETTERSSON B, MOLIN G, UHLÉN M, & AHRNÉ S 1994 Restriction fragment polymorphism of Lactobacillus reuteri and Lactobacillus fermentum, originating from intestinal mucosa, based on 16S rRNA genes. Systematic and Applied Microbiology 17:108-115. 15. GUO W, JOHANSSON M-L, ANDERSSON R, KASRAVI B, WILLÉN R, LIU X, AHRNÉ S, & BENGMARK S 1995 Lactobacillus reuteri does not prevent enteric bacterial translocation following intraperitoneal implantation of rubber drain pieces in the rat. Surgical research Communication 16:247-255. 16. AHRNÉ S, STENSTRÖM I-M, JENSEN N E , PETTERSSON B, UHLÉN M, & MOLIN G 1995 Classification of Erysipelothrix strains on the basis of restriction fragment length polymorphisms. International Journal of Systematic Bacteriology 45:382-385. 17. JOHANSSON M-L, QUEDNAU M, MOLIN G, & AHRNÉ S 1995 Randomly amplified polymorphic DNA (RAPD) for rapid typing of Lactobacillus plantarum strains. Letters in Applied Bacteriology 21:155-159. 18. JOHANSSON M-L, MOLIN G, PETTERSSON B, UHLÉN M, & AHRNÉ S 1995 Characterization and species recognition of Lactobacillus plantarum strains by fragment length polymorphism (RFLP) of the 16S rRNA gene. Journal of Applied Bacteriology 79:536-541. 19. JOHANSSON M-L, QUEDNAU M, AHRNÉ S, & MOLIN G 1995 Classification of Lactobacillus plantarum by restriction endonuclease analysis of total chromosomal DNA using conventional gel electrophoresis. International Journal of Systematic Bacteriology 45:670-675. 20. AHRNÉ S, JOHANSSON M-L, & MOLIN G 1995 Intestinal passage of Lactobacillus rhamnosus DSM 6594 after oral administration in fermented milk. Netherlands Milk and Dairy Journal 49:201-206. 21. PERSSON A, QUEDNAU M, & AHRNÉ S 1995 Composting oily sludges: Characterizing microflora using randomly amplified polymorphic DNA. In: Monitoring and Verification of Bioremidiation. Hinchee R E, Douglas G S, and Ong Say Kee (Eds) Batelle Press, Columbus, Richland, USA. 22. ADLERBERTH I, AHRNÉ S, JOHANSSON M-L, MOLIN G, HANSSON L Å, & WOLD A 1996 A mannose-sensitive adhesin in Lactobacillus plantarum mediating binding to the human colonic cell line HT-29. Applied and Environmental Microbiology 62:2244-2251. 23. MOLIN G, AHRNÉ S, & JOHANSSON M-L 1996 Comparative evaluation of plasmid profiling and ribotyping in the analysis of Lactobacillus plantarum strain heterogeneity in silage: Letters to the Editor. Journal of Applied Bacteriology 80:114115. 24. AHRNÉ S & MOLIN G 1997 Restriction endonuclease analysis of total chromosomal DNA of Lactobacillus. Microecology and Therapy 26:27-30. 25. LINDBERG A-M, LJUNGH Å, AHRNÉ S, LÖFDAHL S, & MOLIN G 1998 Enterobacteriacae found in high numbers in retailed fish, minced meat and pasteurized milk or cream after chill storage, and the presence of toxin encoding genes. International Journal of Food Microbiology 39: 11-17. 26. QUEDNAU M, AHRNÉ S, PETERSSON A-C & MOLIN G 1998 Antibiotic resistant strains of Enterococcus isolated from Swedish and Danish retailed chicken and pork. Journal of Applied Microbiology 84: 1163-1170. 27. QUEDNAU M, AHRNÉ S, PETERSSON A-C, & MOLIN G 1998 Identification of clinically important species of Enterococcus within one day using Randomly Amplified Polymorphic DNA (RAPD). Current Microbiology 36:332-336. 28. JOHANSSON M-L, BERGGREN A, NOBAEK S, NYMAN M, BJÖRCK I, AHRNÉ S, JEPPSSON B, & MOLIN G 1998 Survival of Lactobacillus plantarum DSM 9843 and effect on the short chain fatty acid content in faeces after ingestion of Pro Viva rose hip drink. International Food Microbiology. 42:29-38. 29. AHRNÉ S, NOBAEK S, JEPPSSON B, ADLERBERTH I, WOLD A, & MOLIN G 1998 The normal Lactobacillus flora of healthy human rectal and oral mucosa. Journal of Applied Microbiology. 85:88-94. 30. NIGATU A, AHRNÉ S, GASHE B A & MOLIN G 1998 Randomly Amplified Polymorphic DNA (RAPD) for discrimination of Pediococcus pentosaceus and Pediococcus acidilactici and rapid grouping of Pediococcus isolates. Letters in Applied Microbiology. 26:412-416. 31. MONSTEIN H-G, QUEDNAU M, SAMUELSSON A, AHRNÉ S, ISAKSSON B, & JONASSON J 1998 Division of the genus Enterococcus into species groups using PCR-based molecular typing methods. Microbiology 144: 1171-1179. 32. QUEDNAU M, AHRNÉ S, & MOLIN G 1999 The genomic relationship between Enterococcus faecium strains from different sources and with different antibiotic resistance profiles evaluated by restriction endonuclease analysis of total chromosomal DNA using EcoRI and PvuII. Applied and Environmental Microbiology 65(4) :1777-1780. 33. ADAWI D, MOLIN G, AHRNÉ S, & JEPPSSON B. 1999 Modulation of the colonic bacterial flora affects differently bacterial translocation and liver injury in acute liver injury model. Microbial Ecology in Health and Disease 11: 47-54. 34. CUNNINGHAM-RUNDLES S, AHRNÉ S, BENGMARK S, JOHANN-LIANG R, MARSHALL F, METAKIS L, CALIFANO C, DUNN AM, GRASSEY C, HINDS G, & CERVIA J. 2000 Probiotics and Immune Response. American Journal of Gastroenterology 95:22-25 35. NOBAEK S, JOHANSSON M-L, MOLIN G, AHRNÉ S, & JEPPSSON B. 2000 Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome (IBS). American Journal of Gastroenterology 95:1231-1238. 36. ENEROTH Å, AHRNÉ S & MOLIN G. 2000 Contamination of milk with Gramnegative spoilage bacteria during filling of retail containers. International Journal of Food Microbiology 57:99-106. 37. PETTERSSON B, WANG M, FELLSTRÖM C, UHLÉN M, MOLIN G, & AHRNÉ S. 2000 Phylogenetic evidence for novel and genetically different intestinal spirochetes resembling Brachyspira aalborgi in the mucosa of the human colon as revealed by 16S rDNA analysis. Systematic and Applied Microbiology 23:355-363 38. ENEROTH Å, AHRNÉ S & MOLIN G. 2000 Contamination routes of Gramnegative spoilage bacteria in the production of pasteurised milk, evaluated by Randomly Amplified Polymorphic DNA (RAPD). International Dairy Journal 10:325-331. 39. NIGATU A, AHRNÉ S & MOLIN G. 2000 Temperature-dependent variation in API 50 CH fermentation profiles of Lactobacillus species. Current Microbiology 41:21-26. 40. VASQUEZ A, AHRNÉ S & MOLIN G. 2001 Temporal temperature gradient gel electrophoresis (TTGE) as a tool for identification of Lactobacillus casei, Lactobacillus paracasei, Lactobacillus zeae and Lactobacillus rhamnosus. Letters in Applied Microbiology 32:215-219. 42. ADAWI D, AHRNÉ S & MOLIN G. 2001 Effects of different probiotic strains of Lactobacillus and Bifidobacterium on bacterial translocation and liver injury in an acute liver injury model. International Journal of Food Microbiology 70: 213-220. 43. WANG M, ADAWI D, MOLIN G, PETTERSSON B, JEPPSSON B & AHRNÉ S. 2001 Identification of the translocating bacteria in rats with acute liver injury and their relation to the bacterial flora of the intestinal mucosa APMIS 109: 551-8. 44. MONSTEIN H-J, AHRNÉ S, MOLIN G, NIKPOUR-BADR S & JONASSON J. 2001 Identification of enterococcal isolates by temperature gradient gel electrophoresis and partial sequence analysis of PCR-amplified 16S rDNA variable V6 regions. APMIS 109:209-16. 45. MANGELL P, NEJDFORS P, WANG M, AHRNÉ S, WESTRÖM B, THORLACIUS H & JEPPSSON B. 2002 Lactobacillus plantarum 299v inhibits Escherichia coli-induced intestinal permeability. Digestive Diseases and Sciences 47(3):511-516. 46. ADAWI D, MOLIN G, AHRNÉ S & JEPPSON B. 2002 Safety of the probiotic strain Lactobacillus plantarum DSM 9843 ( = strain 299v ) in an endocarditis animal model. Microbial Ecology in Health and Disease 14: 50-53. 47. MCCRACKEN J V, CHUN T, BALDÉON M. E, AHRNÉ S, MOLIN G, MACKIE R I, & GASKINS R H 2002 TNF-alfa sensitizes HT-29 colonic epithelial cells to intestinal lactobacilli. Experimental Biology and Medicine 227(8):665-670 48. VASQUEZ A, JAKOBSSON T, AHRNÉ S, FORSUM U & MOLIN G. 2002 Vaginal Lactobacillus Flora of Healthy Swedish Women. Journal of Clinical Microbiology 40(8) : 2746-2749 49. OLSSON C, AHRNÉ S, PETTERSSON B & MOLIN G. 2003 The bacterial flora of fresh and chilled-stored pork: analysis by cloning and sequencing of rRNA genes. International Journal of Food Microbiology 83:245-252 50. MACK D, AHRNÉ S, WEI S & HOLLINGSWORTH M. 2003. Inhibition of Escherichia coli in vitro correlates with probiotic induced intestinal Muc2 and Muc3 mucin expression. Gut 32(6): 827-833. 51. OLSSON C, OLOFSSON T, AHRNÉ S & MOLIN G. 2003 The Yersinia HPI is present in Serratia liquefaciens isolated from meat. Letters in Applied Microbiology 37:275-280. 52. OLSSON C, AHRNÉ S, PETTERSSON B & MOLIN G. 2004. DNA based classification of food associated Enterobacteriacae previously identified by Biolog GN Microplates. Systematic and Applied Microbiology 27:219-228. 53. OSMAN N, ADAWI D, AHRNÈ S, JEPPSSON B & MOLIN G. 2004. Modulation of the effect of dextran sulfate sodium-induced acute colitis by the administration of different probiotic strains of Lactobacillus and Bifidobacterium. Digestive Diseases and Sciences 49:320-327. 54. WANG M, AHRNÉ S, ANTONSSON M & MOLIN G. 2004. T-RFLP combined with principal component analysis and 16S rRNA gene sequencing: an effective strategy for comparison of fecal microbiota in infants of different ages. Journal of Microbial Methods 59:53-69. 55. DERRIEN M, ADAWI D, AHRNÉ S, JEPPSSON B, MOLIN G, OSMAN N, STESEPETOVA J, VAUGHAN E, DE VOS WILLEM & OUWEHAND A. 2004. The intestinal mucosa as a habitat of the gut microbiota and a rational target for probiotic functionality and safety. Microbial Ecology in Health and Disease. 16:138144. 56. VÁSQUEZ A, AHRNÉ S, JEPPSSON B & MOLIN G. 2005. Oral administration of Lactobacillus and Bifidobacterium strains of intestinal and vaginal origin to healthy human females: re-isolation from faeces and vagina. Microbial Ecology in Health and Disease. 17:15-20. 57. VÁSQUEZ A, MOLIN G, PETTERSSON B, ANTONSSON M & AHRNÉ S. 2005. DNA-based classification and sequence heterogeneities in the 16S rRNA genes of Lactobacillus casei/paracasei and related species. Systematic and Applied Microbiology. 28:430-441 58. WANG M, AHRNÉ S, JEPPSSON B & MOLIN G. 2005. Comparision of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S rRNA genes. FEMS Microbiology Ecology. 54:219-231. 59. MONSTEIN H-J, OLSSON C, NILSSON I, GRAHN N, BENONI C & AHRNÉ S. 2005. Multiple displacement amplification of DNA from human colon and rectum biopsies: Bacterial profiling and identification of Helicobacter pylori-DNA by means of 16S rDNA-based TTGE and pyrosequencing analysis. Journal of Microbial Methods 63:239-247. 60. AHRNÉ S, LÖNNEMARK E, WOLD AE, ÅBERG N, HESSELMAR B, SAALMAN R, STRANNEGÅRD I-L, MOLIN G & ADLERBERTH I. 2005. The intestinal Lactobacillus flora of Swedish infants. Microbes and Infection 7:12561262. 61. OSMAN N, ADAWI D, AHRNÉ S, JEPPSSON B, & MOLIN G. 2005. Probiotic strains of Lactobacillus and Bifidobacterium affect the translocation and intestinal load of Enterobacteriacae differently after D-galactosamine-induced liver injury in rats. Microbial Ecology in Health and Disease, 17: 40-46. 62. MANGELL P, LENNERNÄS P, WANG M, OLSSON C, AHRNÉ S, MOLIN G,THORLACIUS H. & JEPPSSON B. 2006. Adhesive capability of L. plantarum 299v is important for preventing bacterial translocation in endotoxaemic rats. APMIS 114: 611-618. 63. OSMAN N, ADAWI D, MOLIN G, AHRNÉ S, BERGGREN A & JEPPSSON B. 2006. Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats. BMC Gastroenterology 6: 31-41. 64. HÅKANSSON Å, STENE C, MIHAESCU A, MOLIN G, AHRNÉ S, THORLACIUS H & JEPPSSON B. 2006. Rose Hip and Lactobacillus plantarum DSM 9843 Reduce Ischemia/Reperfusion Injury in the Mouse Colon. Digestive Diseases and Science 51:2094-2101 65. WANG M, MOLIN G, AHRNÉ S, ADAWI D & JEPPSSON B. 2007. High proportions of proinflammatory bacteria on the colonic mucosa in a young patient with ulcerative colitis as revealed by cloning and sequencing of 16S rRNA genes. Digestive Diseases and Science In press. 66. FALK A, OLSSON C, AHRNÉ S, MOLIN G, ADAWI D & JEPPSSON B. 2007. Ileal pelvic pouch microbiota from two former ulcerative colitis patients, analysed by DNA-based methods, were unstable over time and showed the presence of Clostridium perfringens group. Scandinavian Journal of Gastroenterology 42:973-985. 67. ADLERBERTH I, STRACHAN DP, MATRICARDI PM, AHRNÉ S, ORFEI L, ÅBERG N, PERKIN MR, TRIPODI S, HESSELMAR B, SAALMAN R, COATES, AR, BONNANO C, PANETTA V, & WOLD AE. 2007 Gut microbiota and development of atopic eczema in three European birth cohorts. Journal of Allergy and Clinical Immunology 120:343-350. 68. OSMAN N, ADAWI D, AHRNÉ S, JEPPSSON B, & MOLIN G. 2007 Endotoxin and D-galactosamine induced liver injury improved by the administration of Lactobacillus, Bifidobacterium and blueberry. Digestive and Liver Disease 39:849856. 69. OLOFSSON TC, AHRNÉ S & MOLIN G. 2007 The bacterial flora of vacuumpacked cold-smoked salmon at 7oC, identified by direct 16S rRNA gene analysis and pure culture technique. Journal of Applied Microbiology 103:109-119. 70. OLOFSSON TC, AHRNÉ S & MOLIN G. 2007. The bacterial flora of refridgerated beef identified with direct 16S rRNA gene analysis and pure culture technique. International Journal of Food Microbiology In Press 71. FÅK F, AHRNÉ S, LINDEROTH A, MOLIN G, JEPPSSON B, & WESTRÖM B. 2007. Age-related effect of the probiotic bacterium Lactobacillus plantarum 299v on the gastrointestinal function in suckling rats. Digestive Diseases and Sciences In press 72. WANG M, KARLSSON C, OLSSON C, ADLERBERTH I, WOLD AE, STRACHAN DP, MATRICARDI PM, ÅBERG N, PERKIN MR, TRIPODI S, COATES AR, HESSELMAR B, SAALMAN R, MOLIN G, & AHRNÉ S. 2008. Reduced diversity in the early faecal microbiota of infants developing atopic eczema. Journal of Allergy and Clinical Immunology 121(1):129-134. 73. FÅK F, AHRNÉ S, MOLIN G, JEPPSSON B, & WESTRÖM B. 2007. Microbial manipulation of the rat dam results in changed colonization and altered properties of the gut in her offsprings. American Journal of Physiology – Gastrointestinal and Liver Physiology 42: 973-985. 74. FÅK F, AHRNÉ S, MOLIN G, JEPPSSON B, & WESTRÖM B. (2008) Maternal consumption of Lactobacillus plantarum 299v affects gastrointestinal growth and function in the suckling rat. British Journal of Nutrition In press. 75. OSMAN N, ADAWI D, AHRNÉ S, JEPPSSON B, & MOLIN G. (2008) Probiotics and blueberry attenuate the severity of Dextran Sulfate Sodium (DSS) induced colitis. Digestive Diseases and Sciences In press Chapter in books and reviews 1. LÖNNER C & AHRNÉ S 1995 Lactobacillus (Baking) In: Food Biotechnology: Microorganisms. Hui Y K and Khachatourians G G (Eds) VCH Publishers, New York, USA. 2. AXELSSON L & AHRNÉ S 2000 Lactic Acid Bacteria. In: Applied Microbial Systematics, Priest F & Goodfellow M (eds.), Applied microbial systematics. Kluwer Academic Press, Dordrechet, The Netherlands. 3. CUNNINGHAM-RUNDLES S, AHRNÉ S, ABUAV-NUSSBAUM B S & DNISTRIAN A. 2002 Development of immunocompetence: role of micronutrients and microorganisms. Nutritional Reviews, 60(5):S68-S72. Contributions at conferences and seminars. . 1. AHRNÉ S, STÅHL S, & MOLIN G. Plasmid profiles of homofermentative Lactobacillus isolated from meat products. 5th International Congress of Bacteriology and Applied Microbiology, Manchester, September, 1986. Poster 2. AXELSSON L, AHRNÉ S, ANDERSSON M, & STÅHL S. Erythromycin resistance plasmid in Lactobacillus reuteri. Frontiers in molecular genetics, Stockholm University, August 21-23, 1988. Poster 3. AXELSSON L, AHRNÉ S, ANDERSSON M, & STÅHL S. Erythromycin resistance plasmid in Lactobacillus reuteri. The Second Symposium on Lactic Acid Bacteria – Genetics, Metabolism and Applications, Wageningen, September, 1988. Poster 4. AHRNÉ S & AXELSSON L. A host/vector system of Lactobacillus reuteri making shot gun cloning possible in this species. The Third Symposium on Lactic Acid Bacteria – Genetics, Metabolism and Applications, Wageningen, September 17-21, 1990. Poster 5. AHRNÉ S, STÅHL M, & MOLIN G. DNA fingerprinting of Lactobacillus reuteri strains based on polymorphism of DNA encoding 16S rRNA. Conference on Taxonomy and Automated Identification of Bacteria, Prague, September 20-24, 1992. Poster 6. QUEDNAU M, AHRNÉ S, & MOLIN G. Aeromonas and other bacteria in waste water treatment plants. Livsmedel-93, Lund, October 27-28, 1993. Poster 7. JOHANSSON M-L, MOLIN G, PETTERSSON B, UHLÉN M, & AHRNÉ S. Studies on Lactobacillus plantarum using different genetical methods. Livsmedel-93. October 27-28, 1993. Poster 8. JOHANSSON M-L, MOLIN G, PETTERSSON B, UHLÉN M, & AHRNÉ S. Studies of Lactobacillus plantarum using different genetical methods. Identification of Bacteria present trends and future prospects. September 19-22, 1993. Poster 9. JOHANSSON M-L, AHRNÉ S, QUEDNAU M, & MOLIN G. Studies on Lactobacillus plantarum using restriction endonuclease analysis (REA) and Randomly Amplified Polymorphic DNA (RAPD). 7th International Congress of Bacteriology and Applied Microbiology, Prague, July 3-8, 1994. Poster 10. QUEDNAU M, AHRNÉ S, & MOLIN G. Investigation of Aeromonas in waste water treatment plants. 7th International Congress of Bacteriology and Applied Microbiology, Prague, July 3-8, 1994. Poster 11. AHRNÉ S, STENSTRÖM I-M, PETTERSSON B, JENSEN N E, & MOLIN G. Classification of Erysipelothrix by restriction fragment length polymorphisms (RFLPS) of the 16S rRNA gene. 7th International Congress of Bacteriology and Applied Microbiology, Prague, July 3-8, 1994. Poster 12. ADLERBERTH 1, AHRNÉ S, JOHANSSON M-L, MOLIN G, & WOLD A. Identification of a mannose-specific adhesin in Lactobacillus plantarum. The Fifth Symposium on Lactic Acid Bacteria- Genetics, Metabolism and Applications. Veldhoven, September 8-12, 1996. Poster 13. AHRNÉ S & MOLIN G. Restriction endonuclease analysis of total chromosomal DNA of Lactobacillus with special reference to the Lactobacillus casei complex. The Fifth Symposium on Lactic Acid Bacteria- Genetics, Metabolism and Applications. Veldhoven, September 8-12, 1996. Poster 14. JOHANSSON M-L, NOBAEK S, BERGGREN A, JEPPSSON B, AHRNÉ S, NYMAN M, & MOLIN G. Survival of Lactobacillus plantarum DSM 9843 and effect on the short-chain fatty acid content in faeces after ingestion of ProViva. The Fifth Symposium on Lactic Acid Bacteria- Genetics, Metabolism and Applications. Veldhoven, September 8-12, 1996. Poster 15. NIGATU A, AHRNÉ S, BERHANU A, GASHE A, & MOLIN G. Lactic acid bacteria of fermented Kocho from Ethiopia. The Fifth Symposium on Lactic Acid Bacteria- Genetics, Metabolism and Applications. Veldhoven, September 8-12, 1996. Poster 16. AHRNÉ S, NOBAEK S, JEPPSSON B, ADLERBERTH I, WOLD A, & MOLIN G. The predominant Lactobacillus spp. on human oral and rectal mucosa. Mikrobiologidagarna, Linköping, April 17-18, 1997. Poster 17. AHRNÉ S, NOBAEK S, JEPPSSON B, ADLERBERTH I, WOLD A, & MOLIN G. The predominant Lactobacillus spp. on human oral and rectal mucosa. Functional Foods: Designer Foods for the Future, Cork, September 30 – October 2, 1997. Poster 18. NOBAEK S, JOHANSSON M-L, MOLIN G, AHRNÉ S, & MOLIN G. Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome. 1st International meeting om management of human intestinal microflora, probiotics and fibers, Rome, June 19-21, 1998. Oral presentation 19. ADAWI D, JEPPSSON B, AHRNÉ S, & MOLIN G. Modulation of the colonic bacterial flora affects bacterial translocation and liver injury in an acute liver injury model. 1st International meeting om management of human intestinal microflora, probiotics and fibers, Rome, June 19-21, 1998. Oral presentation 20. MANGELL P, NEJDFORS P, AHRNÉ S, WESTRÖM B, & JEPPSON B. Intestinal permeability – impact of E. coli and Lactobacilli. Ussing-möte, Lund, December 2-3, 1998. Poster 21. WANG M, ADAWI D, MOLIN G, PETTERSSON B, JEPPSSON B & AHRNÉ S. Translocating bacteria in D-galactosamine-induced liver injury of the rat. XII International Symposium on Gnotobiology, Stockholm, June 19-24, 1999. Poster 22. AHRNÉ S & MOLIN G. Antibiotic resistance of Enterococcus faecium strains isolated from chicken meat. FOOD MICRO 99, Veldhoven, September 13-17, 1999. Oral presentation 23. OLSSON C, MOLIN G, PETTERSSONB, JEON B H , & AHRNÉ S. Evidence for the presence of the E. coli related vt1 gene in Pseudomonas. XXIV International congress on microbial ecology and disease, San Fransisco, September 22-24, 1999. Oral presentation 24. AHRNÉ S. The intestinal Lactobacillus-flora of children from birth to one year of age. XXVI International congress on microbial ecology and disease, Molecular biology and the intestinal microflora with special emphasis on probiotics, Leeuwenhorst, October 3-6, 2001. Oral presentation 25. VASQUEZ A, AHRNÉ S, JEPPSSON B, & MOLIN G. Vaginala bakteriella stammar som probiotika. Functional Food Science, Lund, October 22-23, 2002. Poster 26. OSMAN N, ADAWI D, AHRNÉ S, JEPPSSON B, & MOLIN G. Effekter av några Lactobacillus- och Bifidobacterium-stammar på DSS-inducerad kolit i kolit. Functional Food Science, Lund, October 22-23, 2002. Poster 27. OLOFSSON T, MANGELL P, MOLIN G, AHRNÉ S, & JEPPSSON B. Bakteriell translocation till mesenteriska lymfknutor i samband med kolonresektion: Kan förbehandling med Lactobacillus plantarum 299v minska translokationen? Functional Food Science, Lund, October 22-23, 2002. Poster 28. WANG M, MOLIN G, PETTERSSON B, DIYA A, JEPPSSON B, & AHRNÉ S. Bakteriefloran på kolonslemhinnan hos en patient med ulcerös kolit, identifierad med hjälp av sekvensanalys av 16S rDNA. Functional Food Science, Lund, October 2223, 2002. Poster 29. AHRNÉ S, LÖNNERMARK E, ADLERBERTH I, MOLIN G, ÅBERG N, HESSELMAR B, SAALMAN R, STRANNEGÅRD I-L, & WOLD A. Tarmflorans laktobaciller hos svenska spädbarn. Functional Food Science, Lund, October 22-23, 2002. Poster 30. OSMAN N, ADAWI D, AHRNÉ S, JEPPSSON B, & MOLIN G. Modulation of the effect of Dextran Sulphate Sodium (DSS)-induced acute colitis by the administration of different probiotic strains of Lactobacillus and Bifidobacterium. The Food, GI-tract Functionality and Human Health Cluster, ProEUHealth, Taormina, March 3-5, 2003. Poster 31. STENE C, HÅKANSSON Å, MIHAESCU A, MOLIN G, AHRNÉ S, THORLACIUS H & JEPPSSON B. Administration of rosehip and Lactobacillus plantarum DSM 9843 reduces lipid peroxidation after colonic ischemia in mice. 39th Congress of the European Society for surgical Research, Athens, Greece. May 12-15, 2004. Poster 32. STENE C, HÅKANSSON Å, MIHAESCU A, MOLIN G, AHRNÉ S, THORLACIUS H & JEPPSSON B. Administration of rosehip and Lactobacillus plantarum DSM 9843 reduces lipid peroxidation after colonic ischemia in mice. Bio Tech Forum, Science Conference, Bella Center, Copenhagen, October 5-7, 2004. Poster 33. MADSEN S M, GLENTING J, VRANG A, RAVN P, RIEMANN H K, ISRAELSSON H, NÖRRELYKKE M R, HANSEN A M, ANTONSSON M, AHRNÉ S, & BECK H C. Cell surface-associated glycolytic enzymes from Lactobacillus plantarum 299v mediate adhesion to human epithelial cells and extracellular matrix proteins. 12th European Congress of Biotechnology, Copenhagen, August 21-24, 2005. Poster 34. MADSEN S M, GLENTING J, VRANG A, RAVN P, RIEMANN H K, ISRAELSSON H, NÖRRELYKKE M R, HANSEN A M, ANTONSSON M, AHRNÉ S, & BECK H C. Cell surface-associated glycolytic enzymes from Lactobacillus plantarum 299v mediate adhesion to human epithelial cells and extracellular matrix proteins. 8th Conference on Lactic Acid Bacteria, The Netherlands, August 28September 1, 2005. Poster Patents Title of patent- Major claim family Inventors Priority Countries of date registration Intestine colonizing lactobacilli Lr271, Lp299 and variants thereof colonising the huamn intestinal mucosa in vivo Molin, Ahrné, Bengmark, Jeppsson. July 25, AU 659669 (1995-101991 03) US 5,474,932 (199512-12) US 5,587,314 (199612-24) US 5,591,428 , (199701-07) SE 9102238-4 (199702-05) JP 2742962, (1998-0206) EP 0554418 , (199803-18) DE, FR, GB, AT, BE, CH, DK, ES, GR, IT, LU, NL, SE NO 306699 (1999-1213) CA 2,091,557, (199912-21) FI 109357 (2002-0715) KR 10-376954 (200303-08) FI-2 110 611 (2003-0228) Lp299v and genetically close strains preventing enteropathogens with mannosesensitive binding mechanisms from binding Restriction in US: patent covering only Lp299v Adlerberth, Ahrné, Jeppsson, Johansson, Molin, Wold March 23, 1995 (24 patents) Epithelial adhesive lactobacilli (16 patents) patent Countries of patent application US 6,159,465, (2000- CA, JP, NO 12-12) AU 702705 (1999-0617) EP 0817640 (2003-0521) AT, CH, DE, ES, FR, GB, IT, SE EE 04097 (2003-0815) PL 184 037 (2003-0830) CN 96 194086 (200402-18) HK 1017989 KR 446 482 (2004-0824) Bifidobakterier Strains of Molin, Bifidobacterium Ahrné, having the ability Jeppson. to survive in the intestinal tract and to produce glutamine in vivo January 31, 2003 SE, US-1, EP Tannase producing strains A composition Molin, comprising one Ahrné, or more tannase- Jeppson. producing strains of L. plantarum or closely related Lactobacillus species having the ability to adhere to human mucosa in combination with tannin April 4, 2003 SE, US-1, EP Vaginal flora Probiotic Lactobacillus strains for improved vaginal health October 10, 2004 SE Immunomodulati n of probiotics Molin, Ahrné, Jeppson, Vasques, Berggren. March Israelsen, 10, Madsen, 2003 Glenting, Vrang, Noerrelycke , Hansen, Ahrne, Molin, Ravn, Beck. US, DK