"Burden and prevention of viral hepatitis in the Arctic region" Hepatitis surveillance system and epidemiology in Northern Sweden ANDERS NYSTEDT Norrbotten County Council, Sweden Norrbotten County Lapland Norrbotten region Norrbotten County Council demography 31 dec 2011 • 98.250 square km (25 % of Swe´s total land area) • Population 248.545 • In Norrbotten 192.525 • In Lapland 56.020 Norrbotten County Council demography 31 dec 2011 • Life expectancy 80,5 Y (F 82,7 Y, M 78,2 Y) • Mean age 43,2 (41,1 Sw) • 9,2 % are born abroad The Hepatitis surveillance system Achoo! Microbiology lab The clinician Dept of Communicable disease control The Hepatitis surveillance system Achoo! Diagnose Inform patient Give ”rules of conduct” lab Microbiology Contact tracing Treat The clinician Dept of Communicable disease control For free Diseases • • • • • • • • • • • • • • • • • • • • • • • • • • campylobacterinfektion difteri fågelinfluensa (H5N1) EHEC (infektion med enterohemorragisk E.coli) giardiainfektion gonorré hepatit A-E hivinfektion infektion med HTLV I eller II klamydiainfektion kolera MRSA (infektion med meticillinresistenta gula stafylokocker) mjältbrand paratyfoidfeber pest infektion med pneumokocker med nedsatt känslighet för penicillin G polio rabies salmonellainfektion shigellainfektion syfilis tuberkulos tyfoidfeber virala hemorragiska febrar exkl. denguefeber och sorkfeber (nefropathia epidemica) smittkoppor sars (svår akut respiratorisk sjukdom) • hepatit A-E • hiv infektion • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • atypisk mykobakterieinfektion botulism (S) brucellos (S) cryptosporidiuminfektion (S) denguefeber echinokockinfektion (S) entamöba histolyticainfektion (S) enterobacteriacae-infektion som producerar ESBL (Extended Spectrum Betalactamase) (ingen klinisk anmälan, anmäls endast från laboratorierna) gula febern GAS (beta-hemolyserande grupp-A-streptokocker), invasiv infektion haemophilus influenzae, invasiv infektion harpest (tularemi) Influensa A(H1N1) 2009 kikhosta (S) legionellainfektion (S) leptospirainfektion listeriainfektion (S) malaria meningokockinfektion, invasiv mässling (S) pneumokockinfektion, invasiv papegojsjuka (S) påssjuka (S) röda hund (S) sorkfeber (nephropathia epidemica) stelkramp trikinos (S) Q-feber vancomycinresistenta enterokocker (VRE) (S) vibrioinfektion exkl. kolera (S) viral meningoencefalit The county council incl. politicians Hospital care Primary health care Inf control Laboratories Patients Dept of Communicable disease control Social services Police Prison system Media Municipalities Veterinary NGO´s The public Hepatitis A HAV acute cases 16 14 12 10 8 6 4 2 0 11 20 10 20 09 20 08 20 07 20 06 20 05 20 04 20 03 20 02 20 01 20 00 20 99 19 98 19 19 97 Norrbotten cases Imported cases Year Average incidence 10 Y: 0,36/100.000 Hepatitis B HBV acute and chronic cases (HBs-ag +) 3 100 2 80 Unknown 60 Norrbotten cases 40 Imported cases 20 Year 11 20 10 20 09 20 08 20 07 20 06 20 05 20 04 20 03 20 02 20 01 20 00 20 99 19 98 19 19 97 0 Acute cases Average incidence 10 Y: 19/100.000 Hepatitis B HBV acute and chronic cases (HBs-ag +) 100 80 Unknown 60 Norrbotten cases 40 Imported cases 20 11 20 10 20 09 20 08 20 07 20 06 20 05 20 04 20 03 20 02 20 01 20 00 20 99 19 98 19 19 97 0 Year Average incidence 10 Y: 19/100.000 Hepatitis C HCV cases (all HCV-ab +) 100 80 Unknown 60 Norrbotten cases 40 Imported cases 20 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 0 Year Average incidence 10 Y: 29/100.000 Hepatitis C HCV cases (all HCV-ab +) 100 80 Unknown 60 Norrbotten cases 40 Imported cases 20 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 0 Year Average incidence 10 Y: 29/100.000 Hepatitis D and E Hepatitis D 3 2 1 0 Imported cases 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Year Hepatitis E 1 All cases 0 1997 1998 1999 2000 2001 2002 2003 2004 Year 2005 2006 2007 2008 2009 2010 2011 HIV HIV - new cases 40 35 30 25 20 15 10 5 0 Female Male 19 98 19 99 20 00 20 01 20 02 20 03 20 04 20 05 20 06 20 07 20 08 20 09 20 10 20 11 HIV 40 35 30 25 20 15 10 5 0 1 1 1 Year Unknown 1 Year 2011 2010 2009 2008 2007 2006 2005 2004 2003 Imported cases 2002 2001 2000 1999 1998 Norrbotten cases 1 2 Transm. route iv drug abuse Sápmi demography • About 2 million people • Sámi people in Sápmi about 91.000 • Sámi people in Sweden about 36.000 • Sámi people in Norrbotten about 18.000 Figures from Prof Per Sjölander at the Southern Lapland Research Department in Vilhelmina Sápmi demography… Who is sámi? • One who, or one who’s parents or grandparents have spoken Sámi language at home • One who’s parents were registered to the Sámi Parliament entitled to vote • One who consider himself to be a Sámi. Viral hepatitis and blood bourne infections among Sámi population in northern Sweden 2002-2011 - cases • HAV 0 • HBV 0 • HCV 1* • HIV 0 …as far as I know… The health condition in the Sami population of Sweden “Early contacts with the western society brought infectious diseases such as smallpox and tuberculosis, while western influence during the last five decades have had more profound effects on the lifestyle causing an increase of lifestyle related western diseases such as cancer, diabetes, stroke, obesity and hypertension.” “Compared to other native populations, the prevalence of infectious diseases appears to be low among the Sami.” “Even though the knowledge is quite incomplete, the Sami does not seem to suffer from infectious diseases more than Swedes in general”. Hassler [email protected]