8.30-9.00 Registration 9.00-9.05 Welcome address, Organizing Committee 9.05-9.45 Signaling via receptors for PDGF and TGFbeta - possible targets for tumor treatment, Carl-Henrik Heldin, Ludwig Institute for Cancer Research, Uppsala 9.45-10.25 Causes and consequences of microRNA dysregulation in cancer Carlo Croce, Ohio State University, Columbus. 10.25-10.55 COFFEE BREAK 10.55-11.35 TGF-beta signal transduction in breast cancer Peter ten Dijke, Leiden University, Leiden. 11.35-11.55 PDGF and PDGF receptors in glioma Monica Nistér, Karolinska Institute, Stockholm. 11.55-12.15 Regulation of cancer progression and drug response by cancer-associated fibroblasts Arne Östman, Karolinska Institute, Stockholm. 12.15-13.15 LUNCH 13.15-13.55 Cell Signaling by Tyrosine Phosphorylation; From Basic Principles to Cancer Therapy, Joseph Schlessinger, Yale University School of Medicine, New Haven. 13.55-14.15 Growth factors, angiogenesis and vascular permeability Christer Betsholtz, Karolinska Institute, Stockholm. 14.15-14.35 Mitochondria, oxidative metabolism and cell transformation Anna Karlsson, Karolinska Institute, Stockholm. 14.35-15.00 COFFEE BREAK 15.00-15.40 Tumor-promoting functions of TGF-beta in progression of cancer Kohei Miyazono, University of Tokyo, Tokyo. 15.40-16.20 PDGF and the initiation of non-CIMP gliomagenesis Eric Holland, Memorial Sloan-Kettering Cancer Center, New York 16.20-16.50 Concluding remarks Bengt Westermark, Uppsala University, Uppsala.