Forskningssamverkan –olika modeller Stockholm, May 23 2017 Amy Leval, Outcomes Research Manager, Med Dr Epidemiologi, Janssen Interactive Visualization - Visualizing Prostate Cancer Testing and Outcomes - Who are we? Olof Akre Markus Aly Sandra Eloranta Amy Leval Johan Liwing Mario Romero Urologist Professor KI Urologist, Ph.D. Karolinska University Hospital Researcher Med. Sci. KI Researcher Janssen Visualization Professor KTH sandra.eloranta @ki.se [email protected] J.com RWE Partnerships Janssen [email protected] e Markus.Aly@ki .se [email protected] [email protected] m To be continued… From collaborative visualization to collaborative analytics OHDSI community •>140 researcher institutions in academia, industry, government, health systems • Common data model (OMOP) •>20 countries •>660 million patients Collaborative analytics – current possibility, future standard? 11 data sources, 4 countries, 250 million patients Common data modell. Dela på protokoll, analysresultat, inte på individdata! Yet another way to collaborate…. 11 12 13 Janssen’s global real world evidence network By analyzing a broader range of parameters, real world evidence research can uncover outcomes, unmet needs and clues to future medical breakthroughs. Janssen is partnering with top institutions world wide to accelerate this new line of research. Sweden Canada Hungary USA Our network aims to: Korea Taiwan Apply scientific best practices Advance methodologies Generate evidence about disease pathways, healthcare delivery, and the effects of medical interventions Support medical decisions and identify new medical breakthroughs 14 Unique opportunity for Nordic life science Real world evidence will impact all phases of medical research and therapeutic development. Thanks to its data infrastructure, the Nordic region can become a hot-spot for advanced medical research by enabling uniquely comprehensive and long term studies. Janssen is partnering with Karolinska Institutet in a major collaborative research initiative that focuses on: Treatment resistant depression Prostate cancer Psoriasis B-Cell malignancies Methodology development Janssen’s real world evidence network also facilitates collaboration in other disease areas, across Nordic institutions. 10% Of all global real world evidence research originates from Sweden. Other Nordic countries are also generating an extensive proportion. 15 Broad collaboration: Johnson & Johnson Innovation + Karolinska Institutet Launched 22 May 2015 A broad and unique industry-academia collaboration in the Nordic region to: • advance medical research • nurture emerging healthcare companies • accelerate development of breakthrough products for improved treatment outcomes To support the collaboration Johnson & Johnson Innovation opened a life science innovation office at Karolinska Institutet. Commercial knowledge Resources Coaching Investment Seed-financing Innovation •Academic focus (KI Innovations AB) Abundance of early-stage science excellence World class life sciences research •Prestige •History Nordic influence “IMI is the world's biggest public-private partnership (PPP) in the life sciences. Through the IMI 2 programme, it has a €3.3 billion budget for the period 2014-2024.” 17 IMI’s Big Data for Better Outcomes (BD4BO) Samverkan – topp 3 checklista 1.Förståelse kring den vetenskapliga frågeställningen 2.Uppskatta kompetens hos olika team - ta in mer extern kompetens vid behov… 3.Kontrakt, och tid för kontrakt och process 19 Samverkan för att utveckla life science Det finns flera modeller 20