PCM task force
Biobanking
Bengt Fundin, PhD
Stockholms medicinska biobank
PCM biobank task force - Challenges
Support
Biobank center of excellence
Supporting care providers, researchers and pharma industry
Preanalytic biobanking
Project
meetings
WWW
Biobank Center
Startup
meeting
Tissue
sampling
Processing
and storage
Steering
group
Access to
samples
Processing
and analysis
Center for sample delivery
Start-up
Sampling
Handling
Storage
Access
Analysis
PCM biobank task force - Challenges
Support
Infrastructure &
resources
Quality
High sample quality within the healthcare system
Health care units
Biobank samples
Hospitals
Emergency
hospitals
University hospitals
Available for healthcare and research, well documented, high quality and
comparable, not dependent of laboratory provider
Healthcare integrated biobanking
Documented samples with high quality for healthcare and research
St Görans sjukhus
Karolinska Solna
Karolinska Huddinge
Södersjukhuset
206 Health
care units
Hospitals
University- and
emergency hospitals
Stockholms
medicinska biobank
<2h
<10h
<24h
Community care
laboratories
Södertälje Sjukhus
Norrtälje Sjukhus
Danderyds Sjukhus
Robotic liquid
handling
Frozen tissue
workstation
Sampling units
Karolinska Universitetslaboratoriet
Unilabs AB
Healthcare integrated biobanking (liquids)
Healthcare infrastructure
Referral
in TakeCare
Transport
in healthcare
infrastructure
Sorting and
centrifugation
Biobank infrastructure
Sample
aliquotation
Freezing
and
registration
Healthcare integrated biobanking (tissue)
Healthcare infrastructure
Referral
in TakeCare
Transport
in healthcare
infrastructure
Assessment
by pathologist
Biobank infrastructure
Biobank
workstation
Freezing
and
registration
PCM biobank task force - Challenges
Support
Infrastructure &
resources
Strategy
Capacity
Quality
4D Breast cancer
Strategy for systematic biobanking within the clinical pathway
Mammography
Post-surgical treatment
Hereditary control
Treatment
Health care unit
Oncology
Assessment
Surgery
Surgery
Investigation
Relapse,
metastasis
Radiology
Pat/Cyt
Diagnostics
Biobanking
Blood
Biopsy
Blood
Surgical biopsy
Blood pre- and post treatment
Biopsies and cells of larger tumors
during treatment
Relapse biopsy,
metastasis
Strategic biobanking as part of cancer program
Rare
diseases
Chronic
disease (4D)
Cancer
Common
disease
Commission
Healthy
All patients
Selection of
patients
All patients
with diagnosis
Selection of
patients
As requested
Screening
At all visits
At strategic
visits during
the health
care process
At strategic
visits during
the health
care process
At one or few
visits
As requested
All or a
selection
National Quality Registries
PCM biobank task force - Challenges
Support
Infrastructure &
resources
Quality
Strategy
Capacity
Networks and
collaborations
Healthcare-integrated biobanking
National networks
Umeå
Healthcare-integrated biobanking
with robotic handling, LIMS and
elektronal referrals
Örebro
Uppsala
Stockholm
Healthcare-integrated biobanking
Linköping
Göteborg
Planning phase (SweLife)
Lund/Malmö
Cancer research programs
National networks
StratCan/Cancer network
Umeå
4D Breastcancer
Cancer Core Europé (CCE)
U-CAN
Örebro
Göteborg
Lund/Malmö
Uppsala
Stockholm
SCAN-B/Breastcancer
Nationell cancerportal (lungcancer)
PCM biobank task force - Deliverables
Current situation
analysis for PCM
biobanking
Business
intelligence and
benchmarking
Prerequisites for
implementation of
biobanking for
PCM
Strategy for
biobankning
within clinical
pathways
Manuals,
templates och
checklists for
biobanking
Training and
education
